Program
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Preliminary Program for Discovery to Development Symposium III (july 12, 2012)
MONDAY, July 2nd
08:30 – 09:00
Registration
09:00 – 09:15
OFFICIAL OPENING – 4th Summer School on Medicines (SSM4)
Denis deBlois, Chairman, SSM4 Scientific Committee
Pierre Moreau, Dean, Faculty of Pharmacy Université de Montréal
Michelle Savoie, Director, Montréal InVivo
Pierre Cordelier, Université Paul-Sabatier/ Oncopole, Toulouse
SESSION 1 : NEW MEDICINES: AN OVERVIEW FROM IDEA TO MARKET
Chairperson: Denis deBlois, Université de Montreal
09:15 – 10:15
Drug discovery
Denis de Blois, Université de Montréal, Québec
10:15 – 10:45
Health Break
10:45 – 11:45
Translational medicine
Denis de Blois, Université de Montréal, Québec
Brian White-Guay, Université de Montreal, Québec
11:45 – 13:15
Lunch
13:15 – 14:30
Clinical development
Brian White-Guay, Université de Montreal, Québec
14:30 – 15:30
Molecules and Money
Jeffery Elliott, Sectoral Asset Management, Montreal
15:30 – 16:00
Health Break
16:00 – 17:00
Evolving models of pharma R&D: Introductory remarks & panel
Philippe Walker, V-P Astra Zeneca R&D
17:00 – 19:00
Welcome Reception in Montreal
TUESDAY, July 3rd
SESSION 2 : DRUG DISCOVERY
Chairperson: Denis de Blois, Université de Montreal
08:30 – 9:15
Target identification and validation
Marc Servant, Université de Montreal
9:15 – 10:00
Assessing target function
Michael A Adams, Queen's University, Kingston, ON
10:00 – 10:30
Health break
10:30 – 11:15
The medicinal chemistry of small molecules
Eric Marsault, Université de Sherbrooke
11:15 – 12:00
Case example: Preclinical development of a molecule with an original mechanism of action against leukemia
Christian Recher, Toulouse
12:00 – 13:30
Lunch
13:30 – 14:15
Biologicals: discovery and development
Jean-François Gauchat, Université de Montréal
14:15 – 15:00
Targeting shifting targets: constraints in the area of antibacterials
Karine Auclair, McGill University
15:00 – 15:30
Health break
15:30 – 16:15
Gene therapy: from preclinical to phase I clinical trials
Pierre Cordelier, Toulouse
16:15 – 17:00
Panel Discussion
WEDNESDAY, July 4th
SESSION 3: NONCLINICAL DEVELOPMENT
Session Chairperson: Brian White-Guay, Université de Montreal
8:30 – 9:15
The absorption, distribution, metabolism and excretion of drugs
Véronique Michaud, Université de Montréal
9:15 – 10:00
Current Trends in Non-Clinical Safety Testing
Simon Authier, CiToxLAB
10:00 – 10:30
Health break
10.30 – 11:15
Unexpected & Unusual Adventures in Chemistry, Manufacturing & Controls
Patrick Colin, Chief Development Officer, GiCare Pharma
11:15 – 12:00
Panel Discussion
12:00 – 13:30
Lunch
SESSION 4: CASE STUDY IN DRUG DISCOVERY AND DEVELOPMENT (I)
Development of GIC-1101: A novel analgesic with dual mechanisms of action
Case Study presented by: Patrick Colin, Chief Development Officer, GiCare Pharma
13:30 – 14:00
Case presentation and outline of challenges
14:00 – 15:00
Group session: Students work in small teams to tackle the challenges
15:00 – 15:30
Health break
15:30 – 17:00
Each team reports / General discussion
THURSDAY, July 5th
SESSION 5 : CLINICAL DEVELOPMENT
Chairperson: Brian White-Guay, Université de Montreal
08:30 – 9:15
ADME in humans : Issues and challenges
Jacques Turgeon, Université de Montreal
9:15 – 10:00
Learning trials : exposure – response and dose selection
Richard Lalonde, Pfizer, USA
10:00 – 10:30
Health break
10:30 – 11:15
Biomarkers in drug development
Patrice Hugo, Senior Global Director, LabCorp Clinical Trials
11:15 – 12:00
Panel Discussion
12:00 – 13:30
Lunch
13:30 – 14:15
Regulatory strategy and interactions: early development
Patrick Colin, GiCare Pharma, Canada
14:15 – 15:00
Regulatory strategy and interactions : late development
Brian White-Guay, Université de Montréal
15:00 – 15:30
Health break
15:30 – 16:15
From discovery to life cycle management: an integrated view of drug development
Robin Goldstein, consultant, Boston
16:15 – 17:00
Panel Discussion
FRIDAY, July6th
SESSION 6: CLINICAL TRIALS
Session Chairperson: Denis Querleu, Université Paul-Sabatier, McGill University
8:30 – 9:15
Late development design, analysis & interpretation of clinical trials
Raymond Bain, Merck USA
9:15 – 10:00
Late clinical development issues and challenges
Ted Reiss, Vanderbilt University, Nashville, USA
10:00 – 10:30
Health break
10.30 – 11:15
Value vigilance: What should we be looking for ?
Pierre Anhoury, Accenture, Toulouse
11:15 – 12:00
Panel Discussion
12:00 – 13:30
Lunch
SESSION 7: CASE STUDY IN DRUG DISCOVERY AND DEVELOPMENT (II)
Discovery of Montelukast: Endpoint / comparator selection; target product profile
Case Study presented by: Ted Reiss, Vanderbilt University, Nashville, USA
13:30 – 14:00
Case presentation and outline of challenges
14:00 – 15:00
Group session: Students work in small teams to tackle the challenges
15:00 – 15:30
Health break
15:30 – 16:15
Each team reports
16:15 – 17:00
How it really happened
SUNDAY, July 8th
9:00
Bus departure for Quebec City
12:00
Free Visit (PM)
19:00
Dinner in Old Quebec
MONDAY, July 9th
SESSION 8: MOLECULAR BIOMARKERS AND DEVELOPMENT OF POINT OF CARE DIAGNOSTICS FOR INFECTIOUS DISEASES
Session Chairperson: Michel G Bergeron, Université Laval
9:00 – 12:00
A medical practice revolution : molecular diagnosis of infectious diseases
Michel G Bergeron, Director and Founder, Centre de Recherche en Infectiologie
12:00 – 13:30
Lunch
SESSION 9: INNOVATIVE VACCINE DEVELOPMENT PLATFORM
Session Chairperson: TBA
13:30 – 17:00
Medicago Research Center
Louis-Philippe Vézina, Medicago Inc.
17:00
Departure for Montreal (bus)
TUESDAY, July 10th
SESSION 10 : PHARMACOGIVILANCE AND RISK MANAGEMENT
Chairperson: Sylvie Perrault, Université de Montréal
08:30 – 9:15
Benefit-risk assessment in clinical decision making
James Brophy, McGill University
9:15 – 10:00
Pharmacovigilance and risk management considerations in Canada
Ariel E. Arias, Ctr for Blood and Tissues Evaluation, Health Canada
10:00 – 10:30
Health break
10:30 – 11:15
Global implementation of pharmacovigilance plans
Gervais Tougas, Novartis , Bâle
11:15 – 12:00
Panel Discussion
12:00 – 13:30
Lunch
SESSION 11 : MARKET ACCESS AND HEALTH TECHNOLOGY ASSESSMENT (HTA)
Chairperson: Jean Lachaine, Université de Montreal
13:30 – 14:15
The path towards reimbursement of pharmaceutical innovations in Canada
Frédéric Lavoie, Pfizer
14:15 – 15:00
Market Access – Third Payer Perspective
Reiner Banken, INESS
15:00 – 15:30
Health break
15:30 – 16:15
HTA methodologies
Jean-Eric Tarride, McMaster University
16:15 – 17:00
Panel Discussion
WEDNESDAY, July 11th
SESSION 12: FINANCING THE VALUE CHAIN
Chairperson: (TBA)
08:30 – 9:15
From innovation to value
Anne-Marie Larose, Hema-Quebec
9:15 – 10:00
New trends in financing opportunities, models for start-ups
Elizabeth Douville, Amorchem
10:00 – 10:30
Health break
10:30 – 11:15
Global financing and partnerships
Elizabeth Stoner, MPM Capital, New-York
11:15 – 12:00
Panel Discussion
12:00 – 13:30
Lunch
SESSION 13: BUSINESS DEVELOPMENT
Chairperson: (TBA)
13:30 – 14:15
Biopharmaceutical Stakeholders: understanding the life science ecosystem
Michelle Savoie, Université de Montréal,
14:15 – 15:00
Pharma vs. Biotech
Luc Vachon
15:30 – 16:15
Panel Discussion
16:15 – 17:00
Poster session
THURSDAY, July 12th
SYMPOSIUM : Facing the current innovation challenges in drug discovery and development
Click here to download the program.
FRIDAY, July 13th
SESSION 14: NEW STRATEGIES
Session Chairperson: Jordi Quintana, Parc Científic de Barcelona
8:30 – 9:15
Genomics: present and future impact
Ivo Gut, Director, Natl Ctr for Genomic Analysis, Barcelona
9:15 – 10:00
Public –Private partnerships (PCB-Chembiobank)
Jordi Quintana, Parc Científic de Barcelona
10:00 – 10:30
Health break
10.30 – 11:15
Pre-competitive research / Open Innovation
Max Fehlmann, CQDM
11:15 – 12:00
Panel Discussion
12:00 – 13:30
Lunch
SESSION 15: CAREER PLANNING
Chairperson: Michelle Savoie, Université de Montréal et Montréal InVivo
13:30 – 14:15
Career profiles in life sciences. What are the opportunities?
Patrick Colin, Chief Development Officer, GiCare Pharma
14:15 – 15:00
Career development: what does it take?
Luc Vachon
15:00 – 16:00
Panel Discussion
16:00 – 16:15
SSM4 Closing comments and overture towards SSM5
Denis deBlois
